高原地区胃癌患者红细胞免疫功能变化的临床研究

CHANGES OF RBC-IMMUNOLOGY IN PATIENTS WITH GASTRIC CANCER AT HIGH ALTITUDE

目的 :探讨高原地区胃癌患者红细胞免疫功能情况 ;方法 :分别测定胃癌病人在手术前后红细胞C3b花环形成试验受体 (C3bRRT)以及红细胞免疫复合物花环试验 (I CRT) ,其结果与正常人做对比 ;结果 :胃癌病人红细胞C3b花环促进率术前下降 ,明显低于正常对照组 (P <0 .0 1 ) ,术后回升。红细胞免疫复合物花环率在手术前高于正常对照组 ,术后明显下降 ,与术前相比有明显差异 (P <0 .0 1 ) ;结论 :高原地区居民患胃癌后 ,其红细胞免疫功能下降 ,行手术治疗有利于免疫功能的恢复。

Objetive:To observe the changes of immune function of RBC in pat ients with gastric carcinoma at high altitude.Methods:The C 3b ,C 3b RRT and ICRT were measured before and after neoplasma resection by Guo Feng test.Results:Level of C 3b RRT-RBC was lower significantly compared with normal control group(P<0.01)before resection but increased after operation oppositely ICRT(P<0.01),Conclusion:RBC immune function is lowed when the patients have a gastric carcinoma,but the function can has a recovery afetr the neoplasma is resected at plateau condition.