甘草及其有效成分的皮肤药理和临床应用

Dermatopharmacology and clinic application of Glycyrrhizae Radix et Rhizoma and its active components

近年来临床上正在试用甘草及其有效成分的制剂治疗各种皮肤病,包括过敏性紫癜、银屑病、湿疹、玫瑰糠疹、荨麻疹、系统性红斑狼疮、小儿丘疹性肢端皮炎样皮疹、带状疱疹、扁平疣、斑秃、白癜风和皮肤色素沉着等。综述甘草提取物及其黄酮类化合物、甘草酸等对变态反应性皮肤病、皮肤肿瘤、病毒性皮肤病、色素沉着等皮肤病的药理作用和临床应用研究进展。

In recent years, in clinic the preparations of Glycyrrhizae Radix et Rhizoma and its active components are being tried to treat various skin diseases, such as anaphylactoid purpura, psoriasis, eczema, pityriasis rosea, urticaria, systemic lupus erythematosus, eruption like papular acrodermatitis of childhood, herpes zoster, verruca plana, alopecia areata, leucoderma, skin pigmentation, etc. Research advances on the dermatopharmacology and clinic application of Glycyrrhizae Radix et Rhizoma as well as its flavonoids and glycyrrhizic acid in allergic dermatosis, tumor of skin, viral dermatosis, pigmentation, etc. are reviewed in this paper.