23，Franco A,Guidotti LG,Hobbs MV,et al.Pathogenic effect on of CD+4 positive helper cell in hepatitis B virus transgenic mice.J Immunol,1997,159(4):2001～2008
34，Lohr HF,Krug S,Herr W,et al.Quantitative and functional analysis of core-specific T-helper cell and CTL activities in acute and chronic hepatitis B.Liver,1998,18(6):405～413
45，Milich DR.Influence of T-helper cell subsets and crossregulation in hepatitis B virus infection.J Viral Hepat,1997,4(2):48～59
56，Tsai SL,Liaw YF,Chen MH,et al.Detection of type-I-like T-helper cells in hepatitis C virus infection:implication for hepatitis C virus chronicity.Hepatology,1997,25(2):449～458
67，Schodel F,Peterson D,Milich D.Hepatitis B virus core and e antigen:immune recognition and used as a vaccine carrier moiety.Intervirology,1996,39(1～2):104～110
78，Milich DR,Schodel F,Hughes JL,et al.The hepatitis B virus core and e antigens elicit different Th cell subsets:antigen structure can affect Th cell phenotype.J Viral,1997,71(3):2192～2201
89，Chow YH,Chiang B1,Lee YL,et al.Development of Th1 and Th2 populations and the nature of immune responses to hepatitis B virus DNA vaccines can be modulated by codelivery of various cytokine genes.J Immunol,1998,160(3):1320～1329
910，Brunel F,Darbouret A,Ronco J.Cationic lipid DC-chol induces an improved and balance immunity able to overcome the unresponsiveness to the hepatitis B vaccine.Vaccine,1999,17(17):2192～2203
1011，Alexander J,Fikes J,Hoffman S,et al.The optimization of helper T lymphocytes(HTL) function in vaccine development.Immunol Res,1998,18(2):79～92
6[3]Chu CM, Liaw YF. Peripheral T-cell subsets in asymptomatic hepatitis B-virus carriers. Cell Immunol, 1986, 98 (2): 533 ～ 537.
7[4]Baroja ML, Sirit FL, Caldera DJ. Anti-CD3-activated T cells from chronic nonviremic HBV carriers are hyperreactive to monocytic accessory signals. Clin Immunol Immunopathol. 1993, 69 (2):180～188.
8[5]Yoffe B, Noonan CA, Melnick JL, et al. Hepatitis B virus DNA in mononuclear cells and analysis of cell subsets for the presence of replicative intermediates of viral DNA. J Infect Dis, 1986,(3):471～477.
9[7]Guidotti LG, Rochford R, Chung J, et al. Viral clearance without destruction of infected cells during acute HBV infection. Science,1999, 284 (5415): 825～829.
10[8]Shen HD, Choo KB, Lee SD, et al. Hepatitis B virus DNA in leukocytes of patients with hepatitis B virus-associated liver diseases. J MedVirol, 1986, 18 (3): 201～211.
