蛋源性抗菌肽的研究进展

Research Progress on Antimicrobial Peptides Derived from Egg Protein

抗菌肽具有分子质量小、热稳定性高、抗菌谱广等特点,已成为生物领域研究的热点之一,而富含蛋白质的禽蛋成为分离天然或制备抗菌肽的研究对象。本文综述蛋源性抗菌肽的来源、抗菌活性以及结构与活性之间的关系,提出蛋源性抗菌肽研究中存在的问题,并对蛋源性抗菌肽的研究与应用进行展望。

Antibacterial peptides are one of the research focuses in biological field,which has several features,such as small molecular weight,high thermal stability and wide antimicrobial spectrum.Naturally,eggs with high content of proteins have become an important source for preparation of antimicrobial peptides.Here we reviewed the antimicrobial peptides derived from egg proteins,its antimicrobial activity and the relationship between peptide structure and antimicrobial activity.At the end,we summarized the problems existing in the study of antibacterial peptides from egg proteins and discussed directions for further study and their potential application in practice.