额瓣整复口腔癌术后缺损的应用和放疗影响

The effect of radiotherapy on reconstructing the defective tissue with forehead flap after oral cancer dissection

目的 探讨额瓣整复口腔癌术后缺损的可行性 ,并研究放疗对其影响。方法 对 8例口腔癌行半程放疗(2 5～ 35Gy)后作口腔癌根治术加额瓣整复术。取瓣面积 4× 5～ 6× 12cm2 。术后三周追加放疗。放疗总剂量 6 5～80Gy。结果 所有病例手术创口Ⅰ期愈合 ,张口度 2 5～ 32mm ,患者 2年和 5年生存率分别为 87.5 % (7/ 8)和 6 6 .7% (4 /6 )。结论 利用额瓣整复口腔癌术后缺损是一种较好的方法。术前、后的半程剂量不会影响皮瓣成活 ,中晚期口腔癌患者采用综合治疗能获得满意疗效。

Objective To discuss the feasibility and effect on reconstructing the defective tissue with pedicled forehead flap after oral cancer dissection.Methods 8 patients with oral cancer treated with preoperative radiotherapy(25～35Gy) underwent primary resection,followed by reconstruction on defective tissue with their forehead flap,whose sizes ranged from 4×5cm to 6×12cm.Then the patients were treated with postoperative irradiation in three weaks with a total dose of 65～80Gy.Results All patients turned out to be at phase Ⅰ with 25 to 32mm width of opening mouth.The 2 year and 5 year survival rates with 87.5%(7/8) and 66.7%(4/6).Conclusions The forehead flap,not affected by half dose preoperative and postoperative radiotherapy,is a good choice for reconstructing defective tissue after oral cancer dissection.For advanced oral cancer combined radiotherapy and surgery is preferred. [