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Potentiometric determination of mefenamic acid in pharmaceutical formulation by membrane sensor based on ion-pair with basic dye 被引量:1

Potentiometric determination of mefenamic acid in pharmaceutical formulation by membrane sensor based on ion-pair with basic dye
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摘要 The characteristics, performance and application of membrane sensors based on ion-pair Brilliant Green mefenamate are described. The sensor's response to the mefenamate ion has the sensitivity of (86.0 ± 2.0) mV/pC over the range of 9 × 10 s-I × 10 2 mol/L and the detection limit of 4.5 ×10 s mol/L at pH 8.5-12. The sensor is easily assembled at a relatively low cost and has fast response time (5-10 s). The proposed sensor displayed good selectivity for mefenamate ion in the presence of different substances. It was used to determine mefenamic acid in pharmaceuticals. The characteristics, performance and application of membrane sensors based on ion-pair Brilliant Green mefenamate are described. The sensor's response to the mefenamate ion has the sensitivity of (86.0 ± 2.0) mV/pC over the range of 9 × 10 s-I × 10 2 mol/L and the detection limit of 4.5 ×10 s mol/L at pH 8.5-12. The sensor is easily assembled at a relatively low cost and has fast response time (5-10 s). The proposed sensor displayed good selectivity for mefenamate ion in the presence of different substances. It was used to determine mefenamic acid in pharmaceuticals.
出处 《Chinese Chemical Letters》 SCIE CAS CSCD 2013年第4期315-317,共3页 中国化学快报(英文版)
关键词 Mefenamic acidPVC membrane sensorsPotentiometryPharmaceutical analysis Mefenamic acidPVC membrane sensorsPotentiometryPharmaceutical analysis
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