肝硬化诱发多脏器功能衰竭的因素及预防探讨

A study on the factors predisposed multiple organ failure and its prevention for patients with liver cirrhosis

目的探讨不同年龄肝硬化患者发生多脏器功能衰竭（ ＭＯＦ）的各种诱发因素和预防。方法比较６０岁以上老年人（Ａ组）与小于６０岁非老年人（Ｂ组）间ＭＯＦ的诱发因素、发生率和死亡率。结果肝硬化失代偿期诱发ＭＯＦ的主要因素老年组为感染，非老年组为出血，且老年组ＭＯＦ的发生率、发生衰竭脏器的数目、病死率均高于非老年组。结论不同年龄肝硬化失代偿期诱发ＭＯＦ的因素不同，而且老年病人更易发生ＭＯＦ，发生后的病死率明显增高。

Aim To investigate the factors predisposed to multiple organ failure(MOF) for patients with liver cirrhosis in different ages and prevention of MOF. Method Factors predisposed to MOF, the morbidity and mortality of MOF were compared between patients more than 60 years old (group A) and that less than 60 years old (group B). Result Infection was a primary factor for MOF in group A while hemorrhage in group B. There were higher morbidity and mortality in group A. Conclusion The aged patients with discompensative hepatic function predisposed to MOF and had a higher mortality.