维生素E对妊娠期高血压病患者血脂浓度的影响

Effects of vitamin E on concentration of lipid in blood serum of patients with hypertensive disorder complicating pregnancy

目的观察维生素E对妊娠期高血压病患者血清中三酰甘油(triacylglycero,TG)、总胆固醇(total cholesterol,TC)、低密度脂蛋白(low-density lipoprotein,LDL)和高密度脂蛋白(high-density lipoprotein,HDL)浓度的影响。方法选取37例妊娠期高血压病患者与30名正常妊娠孕妇,37例妊娠期高血压病患者中21例每日口服维生素E 50 mg直至分娩前,另外16例不做任何处理,30名正常孕妇其中15名每日口服维生素E 50 mg直至分娩前,另外15名不做任何处理,分娩前抽取其静脉血,测定血脂水平。结果口服维生素E组(C组)中血清TG、TC、LDL浓度明显低于未口服维生素E组(D组)与对照组(P<0.05),口服维生素E组中血清HDL浓度明显高于未口服维生素E组(P<0.05)。结论维生素E能显著降低妊娠期高血压疾病患者血清TG、TC、LDL浓度,升高血清HDL浓度。

Objective To investigate the effect of Vitamin E on concentration of TG, TG, LDL, HDL in blood serum of pa- tients with hypertensive disorder complicating pregnancy. Method Thirty - seven women who suffered from gestational hypertension and preeclampsia and 30 normal pregnant women were recruited. 21 of the 37 women took vitamin E 40 mg/d by month in the 37 women, the other 16 women took nothing. 15 of the 30 normal pregnant women took vitamin E 40 mg/d by mouth in, the other 15 women took nothing. Venous blood was taken and lipid was detected before delivery. Results The concentration of TG, TG, LDL in group of taking vitamin E was lower than that in not taking vitamin E group and control group （ P 〈 0.05 ） , The concentration of HDL in group of taking vitamin E was higher than that in not taking vitamin E group （ P 〈 0.05 ）. Conclusions Vitamin E can depresses the concentration of TG, TG, LDL and increases the concentration of HDL.