摘要
探讨有临床表现的狼疮性肾炎 (LN)患者与临床、实验室无肾损害证据的系统性红斑狼疮 (SLE)患者肾脏病理改变及临床意义。分别将有临床表现的LN 34例 ,确诊SLE而血、尿检查无肾脏损害的亚临床LN 2 2例进行肾活检 ,观察两组肾脏病理改变。结果示两组肾小球病损率均为 10 0 % ,且WHO分型两组差异亦无显著性 ,肾小管及间质损害两组发生率接近。提示SLE患者早期肾活检确定病理类型 。
In this artical, the pathologic alterations and clinical significance are described in patients with clinical manifestations of lupus nephritis (LN)(divided as groupA, 34 cases of clinical LN) and in those with systemic lupus erythematosus (SLE) but without renal damage proven by blood or urine tests (divided as groupB, 22 cases of subclinical LN). Renal biopsy had been done in these two groups and observed the pathological alterations in the kidneys. Results showed that damage rates in glomerulus were 100% in both groups, there was no significant difference between clinical LN and subclinical LN by WHO category, and damage in either renal tubule or interstitium was nearly similar in these two groups. It indicated that there has great significance in the primary prevention of renal protection by early renal biopsy to determine the pathological categories, early diagnosis and treatment of subclinical LN.
出处
《右江民族医学院学报》
2000年第5期695-696,共2页
Journal of Youjiang Medical University for Nationalities
关键词
狼疮肾炎
亚临床
病理
临床
lupus nephritis
subclinical
pathology, clinical
