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冠心病患者颈动脉粥样硬化的性别差异

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摘要 目的探讨冠心病患者颈动脉粥样硬化的性别差异,为冠心病的预防及治疗提供参考。方法随机选择2009年1月到2012年1月我院收治的174例冠心病患者做为观察对象,根据性别将174例患者分成两组,及男冠心病组97例,女冠心病组77例。比较两组患者的年龄,血糖,血压,血脂,体质指数(BMI)及高敏C反应蛋白(hs-CRP),同时应用高频多普勒彩色超声检测两组患者的颈动脉内-中膜厚度(IMT)及颈动脉斑块数。结果女冠心病组的年龄,脉压,收缩压,高密度脂蛋白胆固醇(HDL-C)及总胆固醇(TC)均高于男冠心病组(P<0.05),差异有统计学意义;而低密度脂蛋白胆固醇(LDL-C),女冠心病组要低于男冠心病组(P<0.05),差异有统计学意义;女冠心病组的颈动脉内-中膜厚度(IMT)及颈动脉斑块发生率都低于男冠心病组(P<0.05),差异有统计学意义;两组患者的空腹血葡萄糖水平(FPG),餐后两小时血糖(2hPG),舒张压,甘油三酯(TG),体质指数(BMI)及高敏C反应蛋白(hs-CRP)差异无统计学意义(P>0.05)。结论冠心病患者的颈动脉硬化及颈动脉硬化的部分高危因素存在性别差异,在冠心病的预防及治疗中要注意性别的差异。
作者 郭胜
出处 《中国实用医药》 2013年第11期70-71,共2页 China Practical Medicine
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