皮层下动脉硬化性脑病影像学与临床表现(附330例分析)

Clinical and Imaging Diagnosis of Subcortical Arteriosclerotic \;Encephalopathy

目的 :总结皮层下动脉硬化性脑病 (SAE)临床、影像学表现及诊断要点。方法 :收集分析临床资料完整并有 CT扫描的病例 330例 ,其中 5 4例加磁共振成像。结果 :进行性智能障碍是 SAE的主要临床表现 ,CT扫描显示脑内白质区多发低信号灶 ,MRI表现为长 T1 、长 T2 异常信号灶 ,同时合并多发腔隙性脑梗塞和脑萎缩。结论 :CT平扫结合临床是 SAE最简便有效的诊断手段 。

Objective:To study the clinical manifestation and diagnostic criteria by CT scan in patients with subcortical arteriosclerotic encephalopathy(SAE). Method:A complete clinical data and CT scan in 330 cases of SAE were analysis,54 cases had been evaluated by MRI. Results:Progressive recognition impairment was the main clinical [WT5”,6BZ]manifestation of SAE. CT scan showed multiple hypodensity lesions in the cerebral white matter, which were manifested as long T 1 and long T 2 signal in MRI. Lacunar infarction and cerebral atrophy were the lesions frequently found.60% of the patients was complicated with hypertension. Conclusion: Non contrast CT scan combined with clinical manifestation was the most simple and effective way in diagnoses of SAE. MRI was more sensitive to find lacunar infarction in the brain stem and cerebellum.