脑卒中与睡眠呼吸暂停综合征相关性研究

Study on the relationship between stroke and sleep apnea syndrome

目的 :探讨脑卒中与夜间睡眠呼吸暂停综合征 (SAS)的关系。方法 :对 32例脑卒中患者及正常对照组采用多导睡眠图 (PSG)进行多项睡眠生理指标的检测和对比分析。结果 :脑卒中患者睡眠呼吸障碍类型以阻塞性睡眠呼吸暂停 (OSA)、阻塞性睡眠低通气 (OSH)为主。脑卒中组睡眠呼吸暂停低通气指数 (AHI)及低氧时间显著高于对照组 (P <0 0 1) ,夜间血氧饱和度 (SaO2 )明显低于对照组 (P <0 0 1)。睡眠血压曲线呈非杓状。结论 :脑卒中与SAS关系密切 ,SAS是脑卒中发病的危险因素之一 ,可能与睡眠期间反复发作的呼吸暂停和低氧血症引起的血压波动增大、脑血流量减少、血液粘滞度增高、动脉硬化加重有关。

Objective:To investigate the relationship between stroke and nocturnal sleep apnea syndrome.Method:Some sleep physiological markers of the subjects were observed and analyzed by polysomnography(PSG).Result:OSA and OSH are chief types of sleep respiratory disturbance.AHI and hypoxia time are significantly higher( P <0 01)and nocturnal SaO 2 significantly lower( P <0 01)than those in control group.Nocturnal blood pressure curve presented non-Dipper. Conclusion:Stroke is correlated with SAS closely.SAS is one of risk factors in stroke occurance.