慢性上颌窦分泌物的细菌学检验及药敏观察

Observation of bacteriological examination and drug sensitivity for chronic maxillary sinus secretions

目的研究慢性上颌窦炎患者的细菌分布并测定分离菌株对各抗生素的敏感度及耐药性。方法对入院治疗的60例慢性上颌窦炎患者采用鼻内镜下直接采取上颌窦内分泌物进行细菌学及药敏实验。结果细菌培养阳性率为65%(39/60),共培养出48例菌株,其中以金黄色葡萄球菌、肺炎链球菌、表皮葡萄球菌的比例最高,对甲硝唑、头孢曲松及阿莫西林克拉维酸钾的敏感度比较高,对庆大霉素、链霉素和四环素的耐药性最强。结论慢性上颌窦炎临床用药应以细菌药敏实验为主,无条件做药敏试验的,可以首选头孢曲松或甲硝唑等。

Objective To research the distribution of bacteria in patients with chronic maxillary sinusitis and separation and determination of strain on the antibiotic sensitivity and resistance. Methods Maxillary sinus secretions taken directly under Nasal endoscope and took bacteriology and drug sensitivity test for the 60 cases with Maxillary sinusitis in our hospital. Results The positive rate of bacterial culture was 65%（39/60）, there were a total of 48 cases of strains. The Staphylococcus aureus, Streptococcus pneumoniae, Staphylococcus epidermidis was the highest, the susceptibility of ceftriaxone and metronidazole, amoxicillin and clavulanate potassium sensitivity was relatively high, The strongest resistance to gentamicin, streptomycin and tetracycline. Conclusion The clinical medication of chronic maxillary sinusitis should be based on the drug sensitive test of bacteria, Unconditional drug sensitive test, and can be the preferred ceftriaxone or metronidazole.