期刊文献+
任意字段
题名或关键词
题名
关键词
文摘
作者
第一作者
机构
刊名
分类号
参考文献
作者简介
基金资助
栏目信息

长效重组人干扰素的研究进展 被引量：2

原文传递
导出
摘要 干扰素（interferon，IFN）是机体在细菌或病毒刺激下产生的一类细胞因子，是由单核细胞、淋巴细胞以及体细胞所产生的一类糖蛋白，是机体防御体系重要的组成部分。根据细胞来源和受体的不同，干扰素可分为Ⅰ、Ⅱ和Ⅲ型。
作者 袁武梅 郑丽舒
机构地区 中国疾病预防控制中心卫生部医学病毒和病毒病重点实验室
出处 《中华实验和临床病毒学杂志》 CAS CSCD 2013年第2期150-152,共3页 Chinese Journal of Experimental and Clinical Virology
关键词 重组人干扰素 细胞因子 单核细胞 淋巴细胞 防御体系 细胞来源 糖蛋白 体细胞
分类号 R3 [医药卫生—基础医学] R9 [医药卫生—药学]
  • 相关文献

参考文献3

二级参考文献59

  • 1Glue P, Fang JW, Rouzier PR, Raffanel C, Sabo R, Gupta SK,et al. Pegylated interferon-α2b: pharmacokinetics, pharmacodynamics, safety, and preliminary efficacy data. Clin Pharmacol Ther 2000; 68: 556-7.
  • 2Foser S, Schacher A, Weyer KA, Brugger D, Dietel E, Marti S,et al. Isolation, structural characterization, and antiviral activity of positional isomers of monopegylated interferon α-2a(PEGASYS). Protein Expr Purif 2003; 30: 78-87.
  • 3Vanslooten ML, Boerman O, Romoren K, Kedar E, Crommelin DJ, Storm G. Liposomes as a sustained release system for human interferon-γ: Biopharmaceutical aspects. Biochim Biophys Acta 2001; 1530: 134-45.
  • 4Howell SB. Clinical application of a novel sustained-release injectable drug delivery system: DepoFoam^TM Technology. Cancer J 2001; 7: 219-25.
  • 5Kim S, Khatibi S, Howell SB, McCully C, Balis FM, Poplack DG.Prolongation of drug exposure in cerebrospinal fluid by encapsulation into DepoFoam. Cancer Res 1993; 53: 1596-8.
  • 6Kim S, Turker MS, Chi EY, Sela S, Martin GM. Preparation of multivesicular liposomes. Biochim Biophys Acta 1983; 728:339-48.
  • 7Katre NV, Asherman J, Schaefer H, Hora M. Multivesicular Liposome (DepoFoam) technology for the sustained delivery of insulin-like growth factor-1 (IGF-1). J Pharm Sci 1997; 87:1341-6.
  • 8Ye Q, Asherman J, Stevenson M, Brownson E, Katre NV.DepoFoam^TM technology: a vehicle for controlled delivery of protein and peptide drugs. J Control Release 2000; 64: 155-66.
  • 9Mantripragada S. A lipid-based depot (DepoFoam technology)for sustained release drug delivery. Prog Lipid Res 2002: 41:392-406.
  • 10Bilati U, Allemann E, Doelker E. Strategic approaches for overcoming peptide and protein instability within biodegradable nanoand microparticles. Eur J Pharm Biopharm 2005; 59: 375-88.

共引文献32

同被引文献45

  • 1袁新生,张经良.凯因益生联合拉米夫定治疗慢性乙型肝炎的临床研究[J].中国新药杂志,2007,16(4):312-314. 被引量：2
  • 2Pestka S, Krause CD, Walter MR. Interferons, interferon-like cytokines, and their receptors. Immunol Rev, 2004, 202 : 8-32. doi : lO. 111 l/j. 0105-2896. 2004. 00204. x.
  • 3Hertzog PJ. Overview. Type I interferons as primers, activators and inhibitors of innate and adaptive immune responses, hnmunol Cell Biol, 2012, 90: 471-473. doi: 10. 1038/icb. 2012. 15.
  • 4Seagnolari C, Antonelli G. Antiviral activity of the interferon alpha family: biological and pharmacological aspects of the treatment of chronic hepatitis C. Expert Opin Biol Ther, 2013, 13 : 693-711. doi: 10. 1517/14712598. 2013. 764409.
  • 5Van Pesch V, Lanaya H, Renauld JC, et al. Characterization of the murine alpha interferon gene family. J Viral, 2004, 78: 8219-8228. doi: 10. l128/JVI. 78. 15. 8219-8228. 2004.
  • 6Zwarthoff EC, Mooren AT, Trapman J. Organization, struclure and expression of murine interferon alpha genes. Nucleic Acids Res. 1985, 13: 791-804. doi: 10. 1093/nar/13.3. 791.
  • 7Uddin S, Majchrzak B, Woodson J, et al. Activation of the p38 mitogen-activated protein kinase by type I interferons. J Biol Chem. 1999, 274 : 30127-30131. doi : 10. 1074/ jbc. 274.42. 30127.
  • 8Gonzalez-Navajas JM, Lee J, David M, et al. lmmunomodulato7 functions of type I interferons. Nat Rev lmmunol, 2012, 12: 125-135. doi: 10. 1038/nri3133.
  • 9Theofilopouos AN, Baccala R, Beutler B, el al. Type l interferons (alpha/beta) in immunity and autoimmunity. Annu Rev hnmunol, 2005, 23: 307-336. doi: 10,1146/annurev. immunol. 23. 021704. 115843.
  • 10Lavoie TB, Kalie E, Crisafulli CS, et al. Bimling and activity of all human alpha interferon subtypes. Cytokine, 2011, 56: 282- 289. doi: 10. 1016/j. cyto. 2011.07. 019.

引证文献2

二级引证文献12

中华实验和临床病毒学杂志
2013年 第2期

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部