高IgE综合征1例

A Case of Hyper-IgE Syndrome

患儿男,10岁余。全身反复出现肿块和红斑并糜烂10年。血嗜酸性粒细胞3.22×109/L;IgE706.3IU/mL,肿块内脓液培养:金黄色葡萄球菌(+)。淋巴结组织病理:淋巴结正常结构紊乱,大量嗜酸性粒细胞和中性粒细胞浸润,部分区域有肉芽肿性炎症改变。诊断:高IgE综合征。

A ten-year-old boy have been suffered of reemTing systemic swelling, erythema and erosion for 10 years. La-boratory tests shows eosinophils 3.22 × 10^9/ L; lmmunoglolbulin E 706.3 IU/ml, Pus culture within the mass ： staphylococcus aureus （ ＋ ）. Pathology of lymph nodes： normal structural disorder, a large number of eosinophils and neutrophils infiltration, granulomatous inflammatory changes in some areas. Diagnosis： Hv-per-lgE syndrome.