摘要
目的测定蝙蝠葛酚性碱对胃癌细胞SGC-7901增殖的影响。方法通过MTr法和台盼兰法，观察蝙蝠葛酚性碱在不同浓度，不同时间条件下，对胃癌细胞SGC-7901增殖作用的影响。结果蝙蝠葛酚性碱能明显抑制SGC-7901细胞的增殖，并呈剂量和时间依赖关系，随浓度增大和作用时间延长其抑制率呈上升趋势。结论蝙蝠葛酚性碱对胃癌可能具有一定治疗作用。
Objective To determine the effect of phenolic alkaloids of menispermum dauricum on the gastric cancer cell SGC -7901 proliferation. Methods We studied the effect of phenolic alkaloids of menisper- mum at different concentrations and different times on the gastric cancer cell SGC - 7901 proliferation by MTr and trypan blue methods. Results PAMD can obviously inhibit SGC - 7901 cell proliferation, and is dose - and time - dependent relationship with extended periods of concentration increase. Its role and inhibition rate was on the rise. Conclusion PAMD may have some therapeutic effect on gastric cancer.
出处
《实用肿瘤学杂志》
CAS
2013年第2期116-119,共4页
Practical Oncology Journal
基金
黑龙江省科技攻关项目（GC09C405-3）
黑龙江中医药大学“优秀创新人才”课题
黑龙江省中医管理局攻关课题（ZHY12-2059）
关键词
蝙蝠葛酚性碱
胃癌
SGC-7901细胞株
细胞增殖
Phenolic alkaloids of menispermum dauricum （PAMD）
Gastric cancer
SGC - 7901 cellline
Cell proliferation
