不同方式的蓝光疗法在新生儿黄疸治疗中的临床效果比较及原因探讨

The Clinical Efficacy and the Reason of the Different Blue Light Therapy for the Treatment of Neonatal Jaundice

目的:探讨不同方式的蓝光疗法在新生儿黄疸治疗中的临床疗效及疗效差异的原因。方法:将笔者所在医院收治的74例新生黄疸患儿随机分为观察组和对照组,对照组给予持续性蓝光照射+药物治疗,观察组采用间继性蓝光照射+药物治疗,观察两组黄疸消退时间、血清生化指标变化,并判断两组临床疗效。结果:观察组黄疸消退时间为(7.6±2.1)d,TBIL血清含量为(32.3±3.2)μmol/L,临床总有效率为93.1%,对照组黄疸消退时间为(12.8±2.5)d,TBIL血清含量为(89.4±12.3)μmol/L,临床总有效率为70.0%,两组不同指标比较差异均有统计学意义(P<0.05)。结论:间继性蓝光照射能显著缩短黄疸消退时间,降低血清胆红素含量,提高临床疗效。

Objective： To explore the clinical efficacy and the difference of the different blue light therapy in the treatment of neonatal jaundice. Method： 74 eases of jaundice neonates were randomly divided into observation group and the control group in our hospital, the control group was given continuous blue light irradiation and drug treatment, the observation group was given indirect blue light irradiation and drug treatment, to observe the the jaundice subsided time and serum biochemical parameters, and to determine the clinical efficacy.Result： The observation group jaundice time was （ 7.6 ± 2.1 ） d, the TBIL content was （ 32.3 ± 3.2 ） μmol/L, the clinical total effective rate was 93.1%, the control group jaundice time was （ 12.8 ± 2.5 ） d, the TBIL content was （ 89.4 ± 12.3 ）μmol/L, the clinical total effective rate was 70.0%, the difference between the two groups was significantly （ P〈0.05 ）. Conclusion： The indirect blue light irradiation can significantly shorten the jaundice, reduce serum bilirubin levels, improve the clinical efficacy.