三维超声容积对比成像联合C平面成像监测胎儿小脑蚓部发育的研究

Study on the fetal cerebellar vermis using three-dimensional ultrasound VCI-C imaging

目的 研究三维超声容积对比成像联合C平面（VCI-C）技术在检测胎儿小脑蚓部发育中的应用价值。方法 运用三维超声VCI-C技术观察18～36孕周的胎儿小脑蚓部发育情况,测量蚓部前后径、上下径及面积,分析其与孕周的关系。结果 应用三维超声VCI-C扩展成像可以评价蚓部形态的大小,识别蚓部的特征性标志：第四脑室顶点和蚓部裂。三维超声VCI-C技术检测结果显示在胎儿小脑正中矢状面测量小脑蚓部,前后径、上下径及面积与孕周呈正相关,蚓部与脑干夹角为（3.89±1.58）°,整个孕期没有变化。结论 运用三维超声VCI-C技术获得的胎儿小脑蚓部信息,可作为判断胎儿发育参考指标,也为防治胎儿小脑病变提供信息。该技术检测结果较为清晰准确,适合临床推广使用。

Objective To study the application value of three-dimensional transabdominal ultrasound VCI-C imaging in detection of fetal cerebellar vermis.Methods Totally 300 normal fetuses at 18～36 gestation weeks were examined by three-dimensional ultrasound VCI-C imaging to observe the fetal cerebellar vermis.Results The view of three-dimensional ultrasound VCI-C imaging well evaluated the integrity and size of vermis morphous,identified characteristic signs of vermis：the fourth ventricle apex and vermis crack.The brain stem and vermis were almost parallel in normal fetus.The angle between them was （3.89±1.58）°.There was no significant relation between the gestational age and the angle.The craniocaudal diameter,anteroposte diameter and acreage of the cerebellar vermis were positively correlated with gestational age.Conclusion The three-dimensional ultrasound VCI-C imaging could help evaluate the development of the cerebellar vermis and show the information of cerebellar vermis and its surrounding structure.It offers a new method to evaluate the fetal cerebellar vermis.