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靶控输注右美托咪啶对全身麻醉诱导期的影响 被引量:3

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摘要 目的 探究靶控输注右美托咪啶对胸外科手术患者全身麻醉诱导期的影响。方法 将108例进行胸外科全身麻醉手术的患者按数字表法随机分成A、B两组,每组54例,B组采用常规麻醉诱导,A组在常规麻醉诱导的基础上靶控输注右美托咪啶,观察两组的循环变化和应激相关指标变化。结果 A、B组平均动脉压(MAP)在T3、T4时刻[A组:T3(79.04±9.54)mm Hg,T4(68.12±12.81)mm Hg;B组:T3(73.39±9.03)mm Hg,T4(63.94±14.71)mm Hg]较T1时刻[A组:T1(86.72±13.46)mm Hg;B组:T1(85.67±9.93)mm Hg]显著降低,且B组的下降幅度明显大于A组;A、B组皮质醇(Cor)水平T3均比T1时显著降低;两组血糖水平在T4时刻较T1显著降低(均P<0.05)。两组各个时刻的心率(HR)、血氧饱和度(SpO2)、乳酸(Lac)水平差异均无统计学意义(均P>0.05)。结论 靶控输注右美托咪啶能明显减少胸外科手术患者全身麻醉诱导期患者的血流动力学紊乱和应激反应,值得在临床中应用。
出处 《中国基层医药》 CAS 2013年第10期1555-1556,共2页 Chinese Journal of Primary Medicine and Pharmacy
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