补肾化痰通络法加针刺治疗肥胖型多囊卵巢综合征的临床研究

Treating polycystic ovary syndrome with obesity by acupuncture combined with tonifying kidney,reducing phlegm and dredging collateral

[目的]观察补肾化痰通络中药加针刺治疗肥胖型多囊卵巢综合征(PCOS)的临床疗效。[方法]将80例肥胖型PCOS患者随机分为中药组、中药加针刺组各40例。两组均建议运动和饮食控制相结合以减轻体质量,中药组口服补肾化痰通络中药,中药加针刺组中加用针刺治疗。两组均治疗3个月经周期,观察临床疗效,黄体生成素/卵泡刺激素(LH/FSH)、睾酮(T)、血糖(FPG)、胰岛素(FINS)的变化,评估胰岛素抵抗(IR)。[结果]中药加针刺组总有效率为80.0%;中药组总有效率为67.5%。体重指数(BMI)、LH/FSH、T、FINS、IR两组治疗后较治疗前均明显降低(P<0.05),BMI、T、FINS、IR治疗后中药加针刺组明显低于中药组(P<0.05),LH/FSH两组治疗后差异无统计学意义(P>0.05);FPG两组治疗前后差异无统计学意义。[结论]补肾化痰通络中药加针刺治疗肥胖型PCOS临床疗效优于单纯应用中药组。

[Objective] To observe the clinical efficacy of tonifying kidney, reducing phlegm and dredging collateral in treating polycystic ovary syndrome （PCOS） with obesity. [Methods] The 80 patients with PCOS were randomly divided into Chinese medicine group and Chinese medicine plus acupuncture group. Reducing body weight through physical exercise and controlling diet were advised in both groups. Both groups were treated for three menstrual cycles. The hormone, including LH, FSH and FPG were measured and the insulin resistance （IR） was assessed by the fasting insulin （FINS）. [Results] The total effective rate of the Chinese medicine plus acupuncture group was 80.0%, and 67.5% was in the Chinese medicine group only. After treatment BMI, LH/FSH, T, FINS and IR were significantly improved in both groups （P〈0.05）. BMI, T, FINS and IR were significantly lower in Chinese medicine plus acupuncture group compared with the other group （P〈0.05）. LH/FSH and FPG, however, showed no significant difference in both groups （P〉0.05）. [Conclusion] The treatment efficacy of Chinese medicine plus dredging collateral in treating PCOS was superior to the simple application of traditional Chinese medicine.