疏血通注射液治疗急性期脑梗死临床研究

Clinical Observation of Shuxuetong Injection in Treatment of Acute Cerebral Infarction

目的:观察疏血通注射液治疗急性期脑梗死的疗效及其安全性。方法:将45例患者按随机数字表单盲法分为对照组22例和治疗组23例,对照组使用巴曲酶10 U、5 U、5 U加入生理盐水100 mL中,于入院第1天、第3天、第5天各静脉滴注1次。治疗组在对照组的基础上应用疏血通注射液6 mL,加入生理盐水250 mL静脉滴注,每日1次。两组均同时采用营养神经等对症支持治疗。7 d后通过实验室检查判断临床疗效。结果:治疗组凝血酶原时间和纤维蛋白原与对照组比较,差异有统计学意义(P<0.05)。治疗组治疗后血小板计数与对照组比较,差异无统计学意(P>0.05)。结论:疏血通注射液治疗急性期脑梗死,可明显提高临床疗效,且用药安全。

Objective ：To observe the effect and security of Shuxuetong Injection treated on acute cerebral infarction. Methods ：Selected 45 cases inpatients and divided them into two groups randomly. Control group be treated with Batroxobin, Treatment group be treated with Shuxuetong Injection and Batroxobin, and all of them be treated with nutrition nerves and so on. To judge the effect passed through lab inspection after 7 days. Results：There were significant difference between the two groups in PT and FIB before and after the treatment （P 〈 0.05 ）. But there was no difference in PLT （P 〉 0.05 ）. Conclusion： Shuxuetong Injection could raise the effect of acute cerebral infarction, and had medication safety.