难治性癫痫持续状态的研究现状与展望

The research status quo and prospects of refractory status epilepticus

难治性癫痫持续状态(refractory status epilepticus,RSE)是一种严重的神经科危急重症,有着较高的发病率和死亡率。目前还没有统一的诊治指南。本文就近年来有关RSE的流行病学、病因、诊断、发病机制、药物和非药物处理、预后相关因子分析的研究进展做一简要阐述。

Refractory statues epilepticus （RSE）is severe neurological emergency, has a high morbidity and mortality. At pres- ent, there is no uniform guideline on the diagnosis and treatment process. This article focuses on research advance currently about epi- demiology, etiology, clinical diagnosis, pathogenesis, and drug and non-pharmacological approaches, and prognostic factors analysis of RSE.