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原癌基因c-myc与宫颈癌的研究进展 被引量:6

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摘要 c—myc癌基因基因定位于染色体8q24,全长6~7kb,含3个外显子,编码蛋白由49个氨基酸残基组成,分子量达64/67kD。在宫颈癌组织中经常发现c—myc自的过度表达和扩增Ngan采用免疫组化技术对45例正常宫颈组织,38例CINI期,37例CINII期,43例CIN期研究发现:在发育不良的细胞中,c—myc自表达活跃。提示在CIN演进中c—myc自是一个重要的原癌基因。
作者 刘桂玲 岳瑛
出处 《中国老年学杂志》 CAS CSCD 北大核心 2013年第9期2217-2218,共2页 Chinese Journal of Gerontology
关键词 c—myc 宫颈癌
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