舒芬太尼在心脏手术麻醉中应用的研究进展

Research Progress in Application of Sufentanil in Cardiac Surgery Anesthesia

心脏手术应激反应强烈,易造成机体损伤。目前临床主要应用大剂量阿片类药物抑制手术所致的应激反应。舒芬太尼具有镇痛效能强、对心功能影响较小、血流动力学平稳、呼吸抑制轻微等特点,近年来在心脏手术麻醉中的应用日益广泛,包括先天性心脏病手术、冠状动脉旁路移植手术、瓣膜置换手术、快通道心脏麻醉等。现就舒芬太尼在心脏手术麻醉中应用的研究进展予以综述。

Stress reaction is very strong in cardiac surgery, which is likely to cause body injury. At present, large doses of opioids are clinilally applied in inhibiting stress reaction caused by the surgery. Sufen- tanil, a very potent opioid, has good qualities of strong analgesic efficacy, slight effects on cardiac function, hemodynamie stability and less respiratory depression. In recent years, sufentanil has been applied increasingly in cardiac surgery anesthesia, including congenital heart disease surgery, coronary artery bypass grafting, valvereplacement, fast track cardiac surgery anesthesia and so on. Here is to make a review on the progress of stud- ies on application of sufentanil in cardiac surgery.