紫外线联合中药疗法治疗寻常性银屑病的临床疗效观察

Observation on Clinical Effect of Ultraviolet Rays Combined with Traditional Chinese Medicine in Treating Psoriasis Vulgaris

目的:探讨紫外线联合中药疗法治疗寻常性银屑病的临床效果。方法:选取2008年10月至2012年10月在我科治疗的70例寻常性银屑病患者的临床资料进行回顾性分析,平均分成两组,对照组予以复方甘草酸苷60mgivgttqd,观察组则在对照组的基础上加用中药熏洗和窄谱紫外线治疗,比较两组治疗后的效果情况。结果:从临床效果分析,对照组的显效以上率和总有效率分别为54.3%、80%;而观察组的显效以上率和总有效率分别为77.1%、97.1%,两组比较有明显的差异性,P<0.05,有统计学意义。从不良反应发生率分析,对照组治疗后5例出现头晕、厌食,3例出现血压升高,2例出现月经不调;观察组出现3例头晕厌食,5例出现皮肤干燥,有不同程度的色素沉着,1例去除眼罩后引起电光性眼炎。两组的不良反应发生率分别为28.5%、25.7%,两组间无明显差异性,P>0.05,无统计学意义。结论:紫外线联合中药疗法治疗寻常性银屑病临床效果满意,副作用小,为治疗提供了很好的方法。

Objective： To observe the clinical effect of ultraviolet rays combined with traditional Chinese medicine in treating psoriasis vulgaris. Method： The clinical data of 70 patients with psoriasis vulgaris treated in our hospital from October 2008 to October 2012 were analyzed retrospectively. And the patients were divided into 2 groups. The control group were treated with compound glycyrrhizin 60mg ivgtt qd, and the observation group were treated with Chinese herbal fumigation and washing and narrow spectrum ultraviolet on the basis of the control group. Comparing the effect of 2 groups after treatment. Result： Analyzing from the clinical effect, the effective rate above and the total effective rate of the control group were 54.3% and 80%. the observation group were 77.1% and 97.1% respectively. There was an evident difference between 2 groups, P〈0.05, which had statistical significance. Analyzing from the incidence of adverse reactions, in the observation group, there were 3 patients appearing dizziness and anorexia, 3 patients with elevated bloodpressure and 2 patients with irregular menstruation. As for the observation group, there were 3 patients with dizziness and anorexia, 5 patients with dry skin and there were different degrees of pigmentation, and 1 case with electric ophthalmia after the removal of eye. The adverse reaction rate of 2 groups were 28.5% and 25. 7%. There was no evident difference between 2 groups, P〉0.05, which had no statistical significance. Concision：Ultraviolet rays combined with traditional Chinese medicine in treating psoriasis vulgaris has sat- isfied effect and with less side effect, which provides better method for the treatment.