高血压合并心房纤颤的相关危险因素分析及并发动脉粥样硬化的危险性研究

The Related Risk Factors Analysis of Hypertension Complicated with Atrial Fibrillation and the Risk Study on Associated with Atherosclerosis

目的分析高血压合并心房纤颤的相关危险因素以及并发动脉粥样硬化的危险性研究。方法回顾性分析我院近3年收治的126例高血压患者的临床资料,根据患者是否合并心房纤颤分为房颤组和无房颤组,比较两组患者临床资料、血生化指标及颈动脉和心脏彩超结果。结果两组年龄、心功能级别、左心室射血分数、左房内径、脑梗死发生率、超敏C反应蛋白(hs-CRP)、三酰甘油(TG)和低密度脂蛋白胆固醇(LDL-C)比较,差异有统计学意义(P<0.05)。房颤组患者颈动脉内膜中膜厚度(IMI)和斑块检出率明显高于无房颤组,差异有统计学意义(P<0.05)。结论年龄增大和左房内径增大为高血压合并心房纤颤的危险因素。高血压合并心房纤颤可能是导致颈动脉IMI增厚及粥样粥样斑块形成,进而加速心功能的损害和促进脑梗死的发生。

Objective To analysis the risk factors of atrial fibrillation complicated with hypertension and the risk of concurrent atherosclerosis. Methods A retrospective analysis of the clinical data of 126 patients with hypertension who were admitted to hospital for the past three years, according to whether the patients with atrial fibrillation were divided into atrial fibrillation group and without atrial fibrillation group, compared two groups of patients with clinical data, blood biochemical index and carotid artery and heart ultrasound results. Results Two groups of age, grade of heart function, left ventricular ejection fraction, left atrial diameter, cerebral infarction, high sensitive C reactive protein （ hs - CRP）, three glycerol （TG） and low density lipoprotein cholesterol （LDL- C）, the difference was statistically significant （P 〈0. 05）. Real carotid artery intima- media thickness in patients with atrial fibrillation group （IMI） and plaque incidence were significantly higher than those without atrial fibrillation group, the difference was statistically significant （P 〈 0. 05）. Conclusion Increasing age and left atrial enlargement atrial fibrillation risk factors for hypertension. Hypertension and atrial fibrillation may lead to thickening of the carotid intima - media thickness and plaque formation, thereby accelerating the damage of heart function and promote the occurrence of cerebral infarction.