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糖皮质激素冲击治疗结核性脑膜炎的临床疗效分析 被引量:15

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摘要 目的探讨糖皮质激素冲击治疗结核性脑膜炎患者的临床疗效及安全性。方法将我院2011年3月—2012年4月收治的92例结核性脑膜炎患者随机分为观察组和对照组,在常规抗结核治疗的基础上,观察组给予甲泼尼龙静脉滴注,对照组给予地塞米松静脉注射。结果观察组患者总有效率为95.6%,高于对照组的78.3%,差异有统计学意义(P<0.05);观察组患者意识恢复时间、平均发热时间均短于对照组,脑脊液白细胞计数、脑脊液蛋白含量、脑脊液氯化物、脑脊液葡萄糖均高于对照组,差异均有统计学意义(P<0.05);两组患者不良反应发生率比较,差异无统计学意义(P>0.05)。结论糖皮质激素药物冲击治疗结核性脑膜炎疗效确切,且不良反应未见明显增加,值得临床广泛推广和应用。
作者 马秀珍
出处 《实用心脑肺血管病杂志》 2013年第5期93-94,共2页 Practical Journal of Cardiac Cerebral Pneumal and Vascular Disease
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共引文献49

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