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胃腺癌组织中NET1 FHIT Ki67的表达与淋巴结转移的关系及预后生存观察 被引量:3

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摘要 胃癌的发生、发展是多种原癌基因的活化和多种抑癌基因的失活造成的,是多种遗传改变累积的结果。胃癌淋巴结转移(LNM)以及转移程度是影响胃癌预后的最重要因素之一。本研究通过胃腺癌组织中神经上皮细胞转化基因,
出处 《中国药物与临床》 CAS 2013年第5期598-600,共3页 Chinese Remedies & Clinics
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  • 1Sorio C, Baron A, Orlandini S, Zamboni G, Pederzoli P,Huebner K, Scarpa A. The FHIT gene is expressed in pancreatic ductular ceils and is altered in pancreatic cancers. Cancer Res 1999; 59:1308-1314.
  • 2Hadaczek P, Siprashvili Z, Markiewski M, Domagala W,Druck T, McCue PA, Pekarsky Y, Ohta M, Huebner K, Lubinski J. Absence or reduction of Fhit expression in most clear cell renal carcinomas. Cancer Res 1998; 58:2946-2951.
  • 3Werner NS, Siprashvili Z, Fong LY, Marquitan G, Schroder JK, Bardenheuer W, Seeber S, Huebner K, Schutte J, Opalka B.Differential susceptibility of renal carcinoma cell lines to tumor suppression by exogenous Fhit expression. Cancer Res 2000; 60:2780-2785.
  • 4Greenspan DL, Connolly DC, Wu R, Lei RY, Vogelstein JT,Kim YT, Mok JE, Munoz N, Bosch FX, Shah K, Cho KR. Loss of FHIT expression in cervical carcinoma cell lines and primary tumors. Cancer Res 1997; 57:4692-4698.
  • 5Yoshino K, Enomoto T, Nakamura T, Nakashima R, Wada H, Saitoh J, Noda K, Murata Y. Aberrant FHIT transcripts in squamous cell carcinoma of the uterine cervix. Int J Cancer 1998; 76:176-181.
  • 6Birrer MJ, Hendricks D, Farley J, Sundborg MJ, Bonome T,Waits MJ, Geradts J. Abnormal Fhit expression in malignant and premalignant lesions of the cervix. Cancer Res 1999; 59:5270-5274.
  • 7Wu R, Connolly DC, Dunn RL, Cho KR. Restored expression of fragile histidine triad protein and tumorigenicity of cervical carcinoma ceils. J Natl Cancer Inst 2000; 92:338-344.
  • 8Chen YJ, Chen PH, Chang JG. Aberrant FHIT transcripts in hepatocellular carcinomas. Br J Cancer 1998; 77:417-420.
  • 9Schlott T, Ahrens K, Ruschenburg I, Reimer S, Hartmann H,Droese M. Different gene expression of MDM2, GAGE-1, -2 and FHIT in hepatocellular carcinoma and focal nodular hvperplasia. Br J Cancer 1999; 80:73-78.
  • 10Keck CL, Zimonjic DB, Yuan BZ, Thorgeirsson SS, Popescu NC. Nonrandom breakpoints of unbalanced chromosome translocations in human hepatocellular carcinoma cell lines.Cancer Genet Cytogenet 1999; 111:37-44.

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  • 1张继红,姜晶,王彩芹,陈永利,史忠新,石家琛,杨静,高文芝.宫颈癌Ki-67及PCNA表达的比较研究[J].中国热带医学,2006,6(10):1793-1794. 被引量:1
  • 2Moldovan GL,Pfander B,Jentsch S. PCNA the maestro of the replication fork[J].{H}CELL,2007,(04):665-679.
  • 3Ogata DC,Marcondes CA,Tuon FF. Superficial papillary urothelial neoplasms of the bladder (PTA E PT 1):correlation of expression of P53,Ki-67 and CK20 with histologic grade,recurrence and tumor progression[J].Rev Col Bras Cir,2012,(05):394-400.
  • 4Sarafoleanu D,Postelnicu V,losif C. The role of p53,PCNA and Ki-67 as outcome predictors in the treatment of laryngeal cancer[J].J Med Life,2009,(02):219-226.
  • 5Romani C, Calza S, Todeschini P, et al. Identification of optimal ref- erence genes for gene expression normalization in a wide cohort of en- dometrioid endometrial carcinoma tissues [J] . PLoS One, 2014, 9 (12): e113781.
  • 6Wu MJ, Chang CH, Chiu YT, et al. Rictor-dependent AKT activa- tion and inhibition of urothelial carcinoma by rapamycin [ J ] . Urol Oncol, 2012, 30 (1): 69-77.
  • 7Julien LA, Carriere A, Moreau J, et al. mTORC1 -activated S6K1 phosphorylates Rictor on threonine 1135 and regulates mTORC2 signa- ling [J] . nol Cell Siol, 2010, 30 (4): 908-921.
  • 8Zhang F, Zhang X, Li M, et al. mTOR complex component Rictor interacts with PKCzeta and regulates cancer cell metastasis [J] . Cancer Res, 2010, 70 (22): 9360-9370.
  • 9Kaibori M, Shikata N, Sakaguchi T, et al. Influence of Rictor and Raptor Expression of mTOR Signaling on Long-Term Outcomes of Pa- tients with Hepatocellular Carcinoma [J] . Dig Dis Sci, 2015, 60 (4) : 919-928.
  • 10Oneyama C, Kito Y, Asai R,et al. MiR-424/503-mediated Rictor upregulation promotes tumor progression [ J ] . PLoS One, 2013, 8 ( 11 ) : e80300.

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