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缺氧诱导因子-1与肿瘤 被引量：2

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摘要 缺氧是一种常见的生理和病理现象。肿瘤的发生发展依赖于机体内氧气与各种营养物质的供给,但肿瘤细胞的异常过度增殖会导致肿瘤细胞严重缺氧,此时肿瘤细胞需通过自身调节来适应氧气与营养物质的缺乏,进行生长和转移。缺氧诱导因子（HIF）-1是调节细胞缺氧反应的最重要的转录因,
作者 刘杰文 路喜安 郝丽芬 齐广强
机构地区 深圳市罗湖区人民医院病理科 山西医科大学第一医院病理科 山西省中西医结合医院病理科
出处 《中国药物与临床》 CAS 2013年第5期624-625,共2页 Chinese Remedies & Clinics
基金 晋留管办发[2009]9号(104)
关键词 缺氧诱导因子-1 肿瘤细胞 营养物质 病理现象 过度增殖 自身调节 缺氧反应 机体内
分类号 R730.2 [医药卫生—肿瘤]
  • 相关文献

参考文献10

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共引文献37

同被引文献54

  • 1吴强,杨述华,叶树楠.缺氧对骨肉瘤SaOS-2细胞系HIF-1α和VEGF表达的影响[J].中国癌症杂志,2004,14(6):501-504. 被引量：2
  • 2茅文斌,邵增务,裴洪,熊琪.骨肉瘤组织中HIF-1α、iNOS与GLUT-1的表达及其与血管生成的关系[J].中国癌症杂志,2007,17(1):46-49. 被引量：4
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二级引证文献8

中国药物与临床
2013年 第5期

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