TORCH感染与不良妊娠结局的相关性分析

Correlation between TORCH infections and abnormal pregnant outcomes

目的了解TORCH感染与不良妊娠结局间的关系。方法采用捕获ELISA法对900例孕妇血清进行TORCH IgM抗体检测,对阳性孕妇进行追踪,并随访其妊娠结局。结果孕妇血清TORCH IgM抗体总阳性率为4.11%(37/900),其中巨细胞病毒、单纯疱疹病毒、风疹病毒和弓形虫特异性IgM抗体阳性率分别为2.00%(18/900)、0.78%(7/900)、0.44%(4/900)和0.89%(8/900)。31例继续妊娠的孕妇中,不良妊娠结局20例,占64.52%。结论TORCH感染是引起不良妊娠结局的重要危险因素。孕期进行TORCH筛查并给予适当干预,可减少不良妊娠的发生,预防出生缺陷。

Objective To understand the correlation between TORCH infections and adverse pregnancy outcomes, so as to provide recommendations for birth defect interventions. Methods The serum samples from 900 pregnant women were tested for TORCH-IgM by capture ELISA. The women with positive results were followed up and the outcomes of their pregnancies were in- vestigated. Results The total TORCH-IgM positive rate of the pregnant women was 4.11% （37/900）. The IgM positive rates of CMV, HSV I1, RV and TOX were 2.00% （18/900）, 0.78% （7/900）, 0.44% （4/900）, and 0.89% （8/900） respectively. Thirty one TORCH-IgM positive pregnant women continued their pregnancies and 20 of them were found abnormal pregnancy outcomes, aecounting for 64.52%. Conclusion TORCH infections are important risk factors responsible for abnormal pregnant outcomes. The screening of TORCH should be performed during pregnancy, and the appropriate interventions can reduce the occurrence of abnormal pregnancy and prevent birth defects.