摘要
新发现的生物活性肽apelin是APJ受体的天然配体,广泛分布于中枢系统和外周组织。研究表明apelin具有广泛的生理作用。该文总结了近几年来关于apelin在摄食、消化、体液平衡、肥胖和糖代谢等方面所取得的最新进展,并结合本实验室的工作,提出了今后的发展趋势。
Apelin,a recently identified bioactive peptide,is identified as the natural ligand for the APJ receptor,and has a wide distribution in both the central nervous system and peripheral tissues.The current studies show that apelin has extensive physiological functions.This review summarizes the latest progress of apelin on feeding,indigestion,fluid homeostasis,obesity and glucose metabolism etc,and the trend of the research development for the future is proposed.
出处
《中国药理学通报》
CAS
CSCD
北大核心
2013年第4期464-467,共4页
Chinese Pharmacological Bulletin
基金
科技部"重大新药创制"科技重大专项资助项目(No2009ZX09503-017)
