两种经气管插管推注PS方法对NRDS患儿的影响

Comparison between effects of two injection PS method by tracheal intubation in NRDS children

目的:探讨两种推注肺表面活性物质(PS)方法对新生儿呼吸窘迫综合征(NRDS)的影响。方法:将65例NRDS需经气管插管给PS患儿,随机分为观察组35例和对照组30例,观察组使用注射器针头斜刺插入气管导管给药,对照组按照传统方法给药。观察两组患儿给药过程中心率、血氧饱和度、药物反流、呼吸困难改善等情况。结果:观察组给药过程中血氧饱和度及心率下降例数少于对照组,药物反流率明显减少(P<0.01),给药后呼吸困难改善优于对照组(P<0.01)。结论:使用注射器针头直接插入气管导管给药方便易行,可有效减少缺氧发生及药物反流,有利于药物弥散。

Objective：To observe the influence of two injection PS methods by tracheal intubation in NRDS children. Methods：65 cases of NRDS children needed in PS by tracheal intubation were divided into the study group wih 35 cases and the control groups with 30 cases. The observation group used the syr- inge needle punctures into the tracheal catheter to medicine, control group was administered with traditional method. Observed the effect of two groups of children on the central process rate of drug, oxygen saturation, drug reflux, dyspnea improved etc. Results：Comparison of the two groups, the cases of oxygen saturation and heart rate decrease in observation group were less than the control group （ P 〈 0.01 ）. And the time of respiratory difficulties in the study group was shorter than in the control group（ P 〈0.01 ）. Conclusion：The way using syringes needle directly into the trachea catheter delivery is convenient and eas- y, and drugs can be effective in reducing the hypoxic reflux, and it is in favour of drug dispersion.