小儿肝硬化29例临床分析

Clinical Analysis of 29 cases of cirrhosis in children

为探讨乙肝疫苗接种以来儿童肝硬化的发病情况，对２９例小儿肝硬化临床资料进行回顾研究。患病年龄最小３个月，最大１５岁，病程３个月至６年不等。其中，乙肝病毒标志物阳性者９例（３１％），肝豆状核变性８例（２７．１％），提示乙型肝炎肝硬化的发病率仍占首位；小儿肝硬化早期不易发现，定期全面认真体检可减少隐匿性肝硬化的发生。另外，改善营养状况、控制感染，也是减少儿童肝硬化发生的重要环节。

To investigate the morbidity and harmfulness of cirrhosis in children,clinical analysis was performed retrospectively.in 29 hospitalized patients with cirrhosis in children from Oct.1982 to Oct.1999 of them,youngest patients was only 3 months and the eldest was 15 years-old.The courses of illness varied from 3 months to 6 years.Of all 29 cases,9(31.0%) were positive for he patitis B virus marker,8(27.1%) showed Wilson disease,and 8(27.1%)were manifested by congenital malformation of bile duct.The cirrhosis caused by hepatitis B is still the most common.The results suggest that the cirrhosis in children was not easily be found at early stage and more attention should be paid to careful physical examination.For prevention.Further more,control of infection and improvement of the nutritional status are of very importance for reducing the cirrhosis morbidity.