认知功能训练对轻度阿尔茨海默病患者认知能力的影响

Effects of cognitive function training on the cognitive ability of patients with mild Alzheimer＇s disease

目的通过对轻度阿尔兹海默病患者进行认知功能训练，研究认知功能训练对轻度阿尔兹海默病患者的认知能力的影响。方法选取39例65岁及以上且符合人选条件的轻度阿尔兹海默病患者，在接受常规药物治疗基础上进行12w的认知功能训练，采用简易智能精神状态量表（mini-mental state examination，MMSE）、日常生活能力量表（activity of daily living scale，ADL）进行评估，并自身前后对照观察。结果认知功能训练6w后，患者的认知能力有所提高，但MMSE评分和ADL评分变化不明显，认知功能训练12w后，MMSE评分和ADL评分均改善（P〈O．01），差异有统计学意义，患者的认知能力明显进步。结论认知功能训练对轻度阿尔兹海默病患者的认知能力有一定疗效，对于提高患者的认知能力有一定意义。

Objective To study effects of cognitive function training on the cognitive ability of patients with mild Al- zheimer＇s disease.. Methods 39 patients with mild Alzheimer＇s disease over 65 years old were selected. In the acceptance of routine drug therapy, a 12 consecutive weeks of cognitive function training was added. Then Mini-Mental State Examination （MMSE）, Activity of Daily Living Scale （ADL） were used to assess the effects. Results After 6 weeks of cognitive function training, cognitive ability of the patients had improved, but the MMSE scores and ADL scores did not change significantly. After 12 weeks of cognitive function training, MMSE score and ADL score were significantly improved （ P〈0.01 ）. The difference was statistically significant. Cognitive ability of the patients was improved. Conclusions Cognitive function training on patients with mild Alzheimer＇s disease was effective to improve cognitive ability.