pHi监测在急性重症胰腺炎患者中的应用及意义

Changes of gastric intramucosal pH and its clinical significance in patients with acute severe pancreatitis

目的 :探讨胃粘膜内pH值 (pHi)监测在急性重症胰腺炎患者中的应用及其临床意义。方法 :对在临床观察期间收住院的 40例急性重症胰腺炎患者在入院后立刻经鼻插入TRIP -NGS导管并测定pHi,以后每隔 12h测量一次pHi。结果 :并发器官功能衰竭的急性重症胰腺炎患者在器官功能衰竭前 1～ 3dpHi即有显著降低 ,而同期测得的全身氧供指标并未发生明显异常。结论 :在急性重症胰腺炎患者中进行pHi监测具有操作简便、结果可靠等优点 ,对于早期发现局部组织缺氧、尽快采取措施预防器官功能衰竭的发生具有重要临床指导意义。

Objective:We continuously monitor pHi in patients with acute severe pancreatitis to detect early gastrointestinal ischemia which may predict the development of multiple organ failure (MOF).Methods:40 patients with pancreatitis were enrolled in this study,every patient received TRIP-NGS tube through nasal cavity to monitor pHi after acute severe pancreatitis were diagnosed.Data of pHi was collected immediately after insertion and every 12 hours.Results:Patients with acute severe pancreatitis who developed MOF during hospitalization had significant low level of pHi in the first 3 days with normal oxygen delivery. Conclusion:Application of pHi monitor is easy and the results are reliable.It can detect early ischemia of internal organs,so the measure can be taken as soon as possible to prevent organ failure.