摘要
目的 探讨广州市妊娠妇女的输血传播病毒 (TTV )感染情况和 TTV透过胎盘屏障进入胎儿体内 (垂直传播 )的可能性。 方法 应用套式 PCR对 2 5 2例广州市孕妇及其新生儿的配对血清标本进行 TTV DNA扩增。 结果 39例孕妇血清和 4例新生儿脐血清检测出 TTV DNA,孕母TTV感染率为 15 .5 % ,母婴垂直传播率为 10 .2 %。 结论 妊娠妇女存在 TTV感染且可经胎盘传递给胎儿。
Objective To investigate transfusion transmitted virus (TTV) infection in pregnant women and its mother to child transmission via the placenta. Methods A nested polymerase chain reaction (PCR) technique was established to detect TTV DNA in 252 pair of serum samples from mothers and its neonates in Guangzhou city. Results TTV DNA was detected in 39 mothers and 4 their babies, respectively. It showed that the incidence of TTV infection in Guangzhou's pregnant women was 15.5%, and the rate of vertical transmission was 10.3%. Conclusion TTV infection exits in pregnant women population, and TTV can be transmitted into the babies via placenta (vertical transmission).
出处
《中华围产医学杂志》
CAS
2000年第3期156-158,共3页
Chinese Journal of Perinatal Medicine
关键词
肝炎
套式PCR
TTV感染
母婴垂直传播
Blood transfusion
Hepatitis viruses
Disease transmission,vertical
Polymerase chain reaction
