女性感染性疾病指标检测分析

Detection of indicators for female infectious diseases

目的了解西安市不同情形女性感染性疾病指标检测情况,为临床治疗妇科疾患提供参考。方法采用酶联免疫吸附试验(ELISA),对不同年份、不同年龄及不同生理病理状态女性进行乙型肝炎病毒(HBV)、苍白密螺旋体(TP)、丙型肝炎病毒(HCV)及人类免疫缺陷病毒(HIV)进行检测。结果 2003-2009年HBsAb、HB-sAg、TP、HCV及HIV的阳性率分别为50.09%、5.37%、0.61%、0.49%和0.01%,其中HBsAb和TP阳性率随年份增加;从年龄看,HBsAb阳性率≥20岁者随年龄增长而降低,HBsAg阳性率<40岁者随年龄增大而增大,≥40岁者随年龄增长而呈下降态势,TP、HCV阳性率与年龄(15～49岁)成正相关;另外2～14岁组与60～81岁组的HCV阳性率高于其他年龄组;从生理病理状态看,妇科疾患组(43.29%)、不孕组(44.09%)的HBsAb阳性率低于妊娠组(52.22%)、正常体检组(51.32%),HBsAg阳性率妇科疾患组(5.94%)>妊娠组(5.03%)>正常体检组(4.01%)、不孕组(4.42%),TP的阳性率妇科疾患组(1.26%)>正常体检组(0.74%)>不孕组(0.72%)>妊娠组(0.41%)。结论在做好基础工作的同时,要关心年长、妇科疾患和不孕者的乙型肝炎疫苗的接种;警惕高龄女性的HCV感染;积极防治妇科疾患,降低HBsAg、TP的阳性率;关注孕妇减少病原体母婴传播;重视TP的防治,阻止不孕症的发生。

OBJECTIVE To investigate the status of detection of indicators for the infectious diseases in female patients in Xi’an so as to guide the clinical treatment of infectious diseases in gynecology department.METHODS By means of enzyme-linked immunosorbent assay（ELISA）,the hepatitis B virus（HBV）,Treponema pallidum（TP）,hepatitis C virus（HCV） and human immunodeficiency virus（HIV） were detected for the various age groups of female patients with different physiological and pathological conditions.RESULTS From 2003 to 2009,the positive rates of HBsAb,HBsAg,TP,HCV,and HIV were 50.09%,5.37%,0.61%,0.49%,and 0.01%,respectively,and the positive rates of HbsAb and TP increased year by year.For the age,the positive rate of HbsAb in the patients aged more than 20 years old decreased year by year,the positive rate of HbsAg in the patients aged less than 40 years old increased year by year,and the positive rate of the patients aged more than 40 years old decreased year by year.The positive rates of the TP and HCV were positively correlated with the age between 15 and 49 year old.The positive rate of the 2-14 years old age group or the 60-81 years old age group was higher than that of other age groups.And for the physiological and pathological conditions,the positive rates of HBsAb were lower in the gynecological disorders group（43.29%） and the infertility group（44.09%） than in the pregnant group（52.22%） and the normal physical examination group（51.23%）.The positive rate of HBsAg was higher in the gynecological disorders group（5.94%） than in the pregnancy group（5.03%）,normal physical examination group（4.01%）,and the infertile group（4.42%）,and the positive rate of TP was higher in the gynecological disorders group（1.26%） than in the normal physical examination group（0.74%）,the infertile group（0.72%） and the pregnancy group（0.41%）.CONCLUSION It is necessary to pay great attention not only to the basic work but also to the hepatitis B vaccination for the elderly and infertile female patients with gynecological disorders,to keep vigilant to the HCV infections in the elderly female patients and to actively prevent and treat the gynecological disorders so as to reduce the positive rates of HBsAg and TP.And the great importance should be attached to the transmission of pathogens from the mother to the child and to the prevention and treatment of TP so as to prevent the infertility.