摘要
以巯基琥珀酸(MSA)作为稳定剂,在水溶液中合成稳定的CdTe纳米量子点,用紫外-可见荧光分光光度和荧光光谱方法研究了CdTe量子点的发光特性。并将其与鼠抗人AFP抗体连接制备水溶性CdTe-AFP复合物探针,对人肝癌细胞进行标记和成像。结果表明所制备的CdTe-AFP复合物探针对人肝癌细胞成像清晰,在生物医学领域具有重要的应用价值。
Mercaptosuccinic acid capped fluorescent CdTe Quantum dots （QDs） weresynthesized by an aqueous approach and studied by UV-Vis absorption and fluorescence emissionspectra. The as-prepared CdTe QDs were linked to mouse anti-human AFP for the labeling of fixed liver cancer cells. The results have indicated that QDs-CdTe probe was ideal fluorescent markets with excellent spectral properties which was important in the application in biological and medical fields.
出处
《光谱实验室》
CAS
2013年第3期1367-1370,共4页
Chinese Journal of Spectroscopy Laboratory
基金
辽宁省自然基金资助项目(20102221)
辽宁省教育厅资助项目(L2010542)
辽宁省教育厅杰出青年学者成长计划(LJQ2011109)
沈阳市科技局资助项目(F11-262-9-21)
沈阳医学院优秀人才(20113068)
