地佐辛复合丙泊酚用于无痛电子胃镜术的疗效观察

Effect of Dezocine Combined with Propofol on Painless Gastrointestinal Endoscop

目的:观察地佐辛复合丙泊酚用于无痛电子胃镜术中的效果及安全性。方法:将156例行无痛电子胃镜术的患者随机分成两组,即地佐辛复合丙泊酚组(D组)和单用丙泊酚组(P组)。对两组患者的麻醉镇痛效果进行评定、并记录丙泊酚总用量、唤醒时间、定向力恢复时间和苏醒后VAS评分以及麻醉期间的不良反应。结果:D组丙泊酚总用量明显高于P组(P<0.01),D组唤醒时间、定向力恢复时间、留观时间均显著低于P组,D组不良反应低于P组,苏醒后VAS评分及镇痛效果均优于P组,差异有统计学意义(P<0.01)。结论:地佐辛复合丙泊酚应用于无痛电子胃镜术,安全可靠,镇痛效果明显,并发症少,值得临床推广。

Objective： To investigate the effect of dezocine combined with propofol on painless gastrointestinal endoscop. Method： From Jan 2011 to Jan 2012, 156 patients undergoing painless gastrointestinal endoscop were randomly divided into two groups： observed group undergoing the intravenous anesthesia by dezocine combined with propofol, and control group receiving propofol alone. Result： Compared with control group, the dosages of propofol in patients of observed group were significantly reduced; the recovery time, the awake time and observation time were all shorter; the analgesic effects were more satisfying. Also the postoperative VAS pain scores of observed group were lower than that of control group. Conclusion： Dezocine combined with propofol is an ideal method for aesthesia in painless gastrointestinal endoscop and get better effects, and is worthy of clinical application.