中药材中二氧化硫残留量快速测定方法

Establishment of Rapid Determination Method for Residue of Sulfur Dioxide in Traditional Chinese Herbs

目的:建立一种适用于中药材中二氧化硫残留量快速测定的方法。方法:根据活泼金属单质锌在稀盐酸中能还原亚硫酸或亚硫酸盐生成硫化氢,而硫化氢能使乙酸铅试纸变黑的原理,对3大类,6个品种,18个批次的中药材中二氧化硫残留量进行测定,并用2010年版《中国药典》方法进行验证。结果:各批次中药材的硫化铅斑点清晰,与标准比色卡比对,可确定二氧化硫残留量范围。结论:方法简单易行,测定时间短,且装置简单,适用于药材中二氧化硫残留量的快速定性或半定量测定。

Objective： To establish a rapid method for determination of sulfur dioxide residue in Chinese herbal medicines. Method： By the principle of in dilute hydrochloric acid,the active metal zinc could restore the sulfurous acid or sulfite to produce hydrogen sulfide,while hydrogen sulfide could lead acetate test paper strips black.We had determined sulfur dioxide residue in 18 batches（3 categories,6 varieties） of Chinese herbal medicines,and then used the ＇Chinese Pharmacopoeia＇ method to verify this experimental method. Result： PbS spots of each batch of Chinese herbal medicines was clear,then compared with standard color card,you could determine the range of sulfur dioxide residue. Conclusion： This method was simple with short measurement time and simple device,it could be applied to rapid qualitative or semiquantitative determination of sulfur dioxide residues in Chinese herbal medicines.