加味生肌白玉散促进宫颈高频电刀环切术后创面恢复

Modified Shengji Baiyu Powder on Wound Healing after Loop Electrosurgical Excision Procedure

目的:探讨宫颈上皮内瘤变患者宫颈环形电切术(LEEP)后局部外用加味生肌白玉散促进创面愈合的效果。方法:选择307例宫颈病变LEEP术后患者,随机分为治疗组121例、对照组122例、空白对照组63例。治疗组患者宫颈创面局部予加味生肌白玉散换药;对照组予胶原蛋白海绵换药;空白对照组术后局部不予药物,仅随访观察。观察三组间创面愈合情况及愈合时间,阴道流液、流血量及持续时间。结果:治疗组创面愈合时间明显缩短,6周内创面完全愈合者占85.1%,阴道出血时间<7 d者占78.5%。而且阴道流液量明显减少,持续时间缩短。与对照组及空白对照组比较有显著性差异(P<0.05)。治疗过程中未发生不良反应。结论:加味生肌白玉散促进宫颈病变LEEP术后创面愈合的疗效确切,安全可靠,值得应用推广。

Objective： To observe the effect of modified Shengji Baiyu powder on the wound healing after loop electrosurgical excision procedure （LEEP）. Method： All the 307 cases with LEEP were randomly divided into the group of modified Shengji Baiyu powder and the group of collagen sponge, and blank control group.During the period of the wound healing, the total effect, wound healing and healing time, vaginal fluid, bleeding volume and duration were observed. Result： In the group of modified Shengji Baiyu powder, the period of the wound healing and the duration of vaginal discharge were shortened greatly,and the quantity of vaginal discharge was much less than that of blank control group. During the treatment without adverse reactions. Conclusion： It is suggested that modified Shengji Baiyu powder can accelerate the wound healing of LEEP evidently,the exact efficacy of safe and reliable.