银丹心脑通胶囊治疗糖尿病合并高脂血症110例

Yindan Xinnaotong Capsule for Treatment of 110 Cases of Diabetes Mellitus and Hyperlipidemia

目的:研究银丹心脑通胶囊治疗糖尿病合并高脂血症的临床效果,为该类疾病的治疗提供临床方案。方法:将2011年1月-2012年1月入我院治疗的220例糖尿病合并高脂血症患者随机分为两组,对照组在控制饮食、适当运动的基础上,采用二甲双胍进行治疗,治疗组在对照组治疗基础上,加用银丹心脑通胶囊,疗程为8周,治疗结束后比较两组患者的血糖(FPG)、血脂水平、以及临床总有效率。结果:与治疗前比较,两组患者的血糖、血脂、糖化血红蛋白(HbA1c)水平均有明显改善(P<0.05);治疗组患者FPG,HbA1c,甘油三醇(TG),总胆固醇(TC),低密度脂蛋白胆固醇(LDL-C)明显低于对照组,高密度脂蛋白胆固醇(HDL-C)明显高于对照组(P<0.05);治疗组临床总有效率为93.6%,明显高于对照组的66.4%(P<0.05)。结论:银丹心脑通胶囊治疗糖尿病合并高脂血症临床效果显著,改善患者血糖、血脂更明显,临床有效率更高,明显好于单一的二甲双胍治疗,值得临床推广应用。

Objective： To investigated the Yindan Xinnaotong capsule （YXC） for treatment of diabetes and hyperlipidemia, to provide therapeutic remedy for treating diabetes and hyperlipidemia. Method： Two hundred and twenty patients from Jan 2011 to Jan 2012 were studied, they were divided into two groups randomly. The control was given metformin on the basis of diet control and moderate exercises. The treatment group was received YXC on the basis of the control remedy. The therapeutic course was 8 weeks, the fasting plasma glucose （FPG）, the lipid levels, glycosylated hemoglobin （HbA1c） and the total clinical effect were compared after treatment. Result： FPG, the lipid levels and HbA1c in two groups were significantly improved after treatment （P〈0.05）. FPG, HbA1c, triglyceride （TG）, total cholestrol （TC） and low density lipoprotein-C （LDL-C） were lower than control, while HDL-C was significant higher （P〈0.05）. The total clinical effect was 93.6% and 66.4% in treatment group and control group accordingly （P〈0.05）. Conclusion： The effect of YXC in treatment of diabetes mellitus and hyperlipidemia is remarkable, the blood sugar and lipid levels were improved, more obvious clinical efficient, higher significantly compared with single metformin treatment. It is worth clinical application.