期刊文献+
任意字段
题名或关键词
题名
关键词
文摘
作者
第一作者
机构
刊名
分类号
参考文献
作者简介
基金资助
栏目信息

内酯类新抗生素泰拉霉素的研究进展 被引量：2

Research Advance of Novel Macrolide Antibiotic Tulathromycin
下载PDF
导出
摘要 泰拉霉素是动物专用半合成大环内酯类抗生素,对于防治猪和牛的呼吸系统疾病疗效确切。从泰拉霉素的理化性质、作用机制、抗菌活性、药动学和药效学、急慢性毒性及药物残留等方面进行综述,旨在为该药在兽医临床应用提供参考资料。 Tulathromycin is a novel semisynthesis macrolide antibiotic for animals which has definite effect in the prevention and treatment of swine and bovine respiratory disease.The physicochemical property,spectrum of activity,mechanisms of action,pharmacokinetics and pharmacodynamics,acute or chronic toxicity and residue of tulathromycin were reviewed,which will provide reference for veterinary clinical application.
作者 郝智慧 孙亚磊 姚德勇 赵永达
机构地区 青岛农业大学化学与药学院 青岛康地恩药业股份有限公司 国家动物用保健品工程技术中心
出处 《安徽农业科学》 CAS 2013年第7期2958-2960,3068,共4页 Journal of Anhui Agricultural Sciences
关键词 泰拉霉素 药动学 药效学 残留 Tulathromycin Pharmacokinetics Pharmacodynamics Residue
分类号 S852.6 [农业科学—基础兽医学]
  • 相关文献

参考文献23

  • 1宋福杰,刘明春,邹美,符特.兽用抗菌药物土拉霉素研究进展[J].兽药与饲料添加剂,2006,11(4):4-6. 被引量：8
  • 2EBERHARD S A,JANINA S A,MONICA V B,et al.Quantitative determi-nation of the macrolide antibiotic tulathromycin in plasma and bronchoalve-olar cells of foals using tandem mass spectrometry[J].Journal of Chroma-tography B,2007,850(1/2):464-470.
  • 3BENCHAOUI H A,NOWAKOWSKI M,SHERINGTON J,et al.Pharmaco-kinetics and lung tissue concentrations of tulathromycin in swine[J].Vet-erinary Pharmacol and Therapeutics,2004,27(4):203-210.
  • 4闫彩虹.新型动物专用抗生素泰拉菌素研究进展[J].畜禽业,2009,20(10):19-21. 被引量：5
  • 5EVANS N A.Tulathromycin:an overview of a new triamilide antimicrobial forlivestockrespiratory disease[J].Veterinary Therapeutics,2005,6(2):83-95.
  • 6NORCIA L J L,SILVIA A M,SANTORO S L,et al.In vitro microbiologicalcharacterization of a novel azalide,two triamilides and an azalide ketal a-gainst bovine and porcine respiratory pathogens[J].J Antibiot,2004,57(4):280-288.
  • 7GODINHO K S,KEANE S G,NANJIANI I A,et al.Minimum inhibitoryconcentrations of tulathromycin against respiratorybacterial pathogens isola-ted from clinical cases in European cattle and swine and variabilityarisingfrom changes in in vitro methodology[J].Veterinary Therapeutics,2005,6(2):113-121.
  • 8亢继俊,王丽霞,曾振灵.动物专用大环内酯类新药——泰拉霉素[J].广东畜牧兽医科技,2010,35(2):7-10. 被引量：10
  • 9MCKELVIE J,MORGAN J H,NANJIANI I A,et al.Evaluation of tulathro-mycin for the treatment of pneumonia followingexperimental infection ofswine with Mycoplasma hyopneumoniae[J].Veterinary Therapeutics,2005,6:197-202.
  • 10NOWAKOWSKI M A,INSKEEP P B,RISK J E,et al.Pharmacokineticsand lung tissue concentrations of tulathromycin,a new triamilide antibiot-ic,in Cattle[J].Veterinary Therapeutics,2004,5(1):60-74.

二级参考文献44

  • 1宋福杰,刘明春,邹美,符特.兽用抗菌药物土拉霉素研究进展[J].兽药与饲料添加剂,2006,11(4):4-6. 被引量：8
  • 2Godinho K S,Keane S G,Nanjiani I A,et al. Minimum Inhibitory Concentrations of Tulathromycin against Respiratory Bacterial Pathogens Isolated from Clinical Cases in European Cattle and Swine and Variability Arising from Chang.es in vitro Methodology [J]. Vet Ther,2005,6(2) :113 -121.
  • 3Reese C P,Norcia L J ,Skogerboe T L,et al. Time - killing Kinetics and Impact of Culture Conditions (pH , CO2 and serum) om MIC Values of Tulathromycin against Hameophilus Sonmus [ D ]. Proc 23rd World Buiatries Congr,2004:70 -71.
  • 4Nowakowski M A,Inskeep P B, Risk J E,et al. Pharmacokinetics and Lung Tissue Concentrations of Tulathromycin, a New Triamilide Antibiotic in Cattle[ J]. Vet Ther,2004, 5 (1) :60 - 74.
  • 5Benchaoui H A, Nowakowski M, Sherington J ,et al. Pharmacokinetics and Lung Tissue Concentrations of Tulathromycin in Swine [J]. Vet Pharmaeol Ther,2004,27(4) :203 -210.
  • 6Eberhard Scheuch A, Janina Spieker A, Monica Venner B, et al. Quantitative Determination of the Macrolide Antibiotic Tulathromycin in Plasma and Broncho - alveolar Cells of Foals Using Tandem Mass Spectrometry [ J].Journal of Chromatography B, 2007,850 : 464 - 470.
  • 7Nutsch R G, Hart F J, Rooney K A,et al. Efficacy of Tulathromycin Injectable Solution for the Treatment of Naturally Occurring Swine Respiratory Disease [ J ]. Vet Ther, 2005,6 ( 2 ) : 214 - 224.
  • 8McKelvie J,Morgan J H,Nanjiani I A,et al. Evaluation of Tulathromycin for the Treatment of Pneumonia Following Experimental Infection of Swine with Mycoplasma Hyopneumoniae [ J ]. Vet Ther,2005,6( 2 ) : 197 - 202.
  • 9Skogerboe T L, Rooney K A, Nutsch R G, et al. Comparative Efficacy of Tulathromycin Versus Florfenicol and Tilmicosin against Undifferentiated Bovine Respiratory Disease in Feedlot Cattle[ J]. Vet Ther,2005,6(2) : 180 - 196.
  • 10Nutsch R G, Skogerboe T L, Rooney K A, et al. Comparative Efficacy of Tulathromycin, Tilmicosin and Florfenicol in the Treatment of Bovine Respiratory Disease in Stocker Cattle [ J ]. Vet Ther,2005,6 ( 2 ) : 167 - 179 .

共引文献21

同被引文献25

  • 1舒刚,李英伦,熊浩山.鸡单剂量内服替米考星的药代动力学研究[J].中国家禽,2004,26(z1):79-81. 被引量：7
  • 2Nowakowski M A, Inskeep P B, Risk J E, et al. Pharmacokinetics and lung tissue concentrations of tulathromycin, a new triamilide antibiotic, in cattle[ J]. Veterinary Therapeutics ,2004,5( 1 ) :60-74.
  • 3Nanjiani I A, Basano F S, Nazzari R. Comparative efficacy of tulathromycin vs. floffenicol/flunixin combination in bovine respiratory disease (BRD) associated with mannheimia haemolytica, pasteurella multocida and histophilus somni, on Italian Commercial Farms [ J ]. Cattle Practice, 2010,18:38-39.
  • 4Young G, Smith G W, Leavens T L, et al. Pharmacokinetics of tulathromycin following subcutaneous administration in meat goats [ J ]. Research in Veterinary Science, 2010, doi : 10.1016/j.rvsc.2010.06.025.
  • 5Scheuch E, Spieker J, Venner M, et al. Quantitative determination of the macrolide antibiotic tulathromycin in plasma and bronchoalveolar cells of foals using tandem mass spectrometry [ J ]. Journal of Chromatography B, 2007,850 : 464- 470.
  • 6Young G, Smith G W, Leavens T L, et al. Pharmacokinetics of tulathromycin following subcutaneous administration in meat goats [ J ]. Research in Veterinary Science,2011,90(3) :477-479.
  • 7Wang X,Tan Y F, Huang L L,et al. Pharmacokinetics of tulathromycin and its metabolite in swine administered with an intravenous bolus injection and a single gavage[ J ]. Journal of Veterinary Pharmacology and Therapeutics ,2011,35:282-289.
  • 8Clothier K A,Leavens T, Griffith R W, et al. Pharmacokineties of tulathromycin after single and multiple subcutaneous injections in domestic goats (Capra aegagrus hircus) [ J]. Journal of Veterinary Pharmacology and Therapeutics,2011,34:448-454.
  • 9Amer A M M, Constable P D, Goudah A, et al. Pharmaeokineties of tulathromycin in lactating goats [ J ]. Small Ruminant Research, 2012,108: 137-143.
  • 10Romanet J, Smith G W, Leavens T L, et al. Pharmacokinetics and tissue elimination of tulathromycin following subcutaneous administration in meat goats [ J ]. American Journal of Veterinary Research, 2012,73 (10) : 1634 - 1640.

引证文献2

二级引证文献1

安徽农业科学
2013年 第7期

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部