摘要
目的:探讨厄贝沙坦对老年高血压患者脉压的影响。方法:选择1~2级老年高血压患者49例,给予厄贝沙坦80mg/天口服,共6个月。观察患者治疗前后脉压、收缩压、舒张压变化和药物的不良反应。结果:与治疗前相比,治疗后患者的脉压缩小(P<0.001)、收缩压和舒张压明显下降(P<0.001),无明显不良反应。结论:厄贝沙坦能缩小老年高血压患者的PP,有效、安全降低血压,从而抗动脉粥样硬化。
Objective: To investigate the influences of irbesartan on Pulse Pressure (PP) in elderly patients with essential hyper- tensine. Methods: 48 elderly patients with essential hypertension were treated with irbesartan 80mg/d for 6 months. The PP were de- tected before and after treatment, as well as systolic blood pressure (SBP) and diastolic blood pressure (DBP). The side effects of irbesartan were observed also. Results: After 6 months of treatment with irbesartan , the PP decreased significantly ( P 〈 0. 01 ), the SEP and DBP decreased significantly (P 〈0. 01 ), and there were no side effects of irbesartan during treatment. Conclusion: irbesartan can decline PP in elderly patients with essential hypertension , lower blood pressure effectively.
出处
《中国民族民间医药》
2013年第7期100-100,102,共2页
Chinese Journal of Ethnomedicine and Ethnopharmacy
关键词
厄贝沙坦
老年
高血压
脉压
Irbesartan
Essential hypertension
Elderly
Pulse pressure (PP)