胸腺瘤的外科手术及临床疗效分析

Surgical Treatment and the Clinical Curative Effect Analysis of the Thymoma

目的探讨胸腺瘤的外科手术治疗方法以及安全性分析。方法通过对本院2006年1月至2008年5月35例胸腺瘤患者进行回顾性分析总结。结果 35例患者其中肿瘤完整切除30例,占85.71%,部分切除5例,占14.29%;随访4年,复发2例,占5.71%。35例中合并重症肌无力26例,占74.29%,术后重症肌无力症状消失11例,占42.31%(11/26),症状缓解12例,占46.15%(12/26);症状无改善甚至加重3例,占11.54%(3/26)。结论重症肌无力是胸腺瘤常见的并发症,手术是治疗胸腺瘤的主要手段,同时根据胸腺瘤分期的差异确定手术切除的范围。

Objective To probe the surgical treatment of thymoma and analysis the security of the treatment. Methods Retrospective analysis and summarize the data from January,2006 to May,2008 of the 35 patients with thymoma in our hospital. Results in the 35patients, there are 30 patients with complete resection of tumor, accounting for 85.71%,and 5 cases have been taken partial resection, which accounting for 14.29%; then the patients had been followed for 4 years, 2 cases had recurrence, which accounting for 5.71%. There are 26 cases of the patients have combine myasthenia gravis, accounting for 74.29%, after the surgical treatment, symptoms of myasthenia gravis disappeared in 11 cases, accounting for 42.31% （11/26） , and symptoms alleviated in 12 cases, accounting for 46.15% （12/26） ; the symptoms did not improved or even aggravated in 3 cases, accounting for 11.54% （3/26） . Conclusion Myasthenia gravis is a common concomitant disease in the patients with thymoma. Surgical treatment is the main method to cure thymoma, and the scope of the surgical resection determined according to the period of thymoma.