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盐酸昂丹司琼对呕吐家兔胃肠激素和神经递质水平的影响研究 被引量:2

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摘要 目的探讨盐酸昂丹司琼对呕吐家兔胃肠激素和神经递质水平的影响。方法选取30只顺铂诱导呕吐家兔为研究对象,将其随机分为A组(空白对照组)、B组(中成药组)和C组(盐酸昂丹司琼组)每组各10只,后将三组家兔的呕吐发生率、呕吐次数、呕吐潜伏期及用药前后的血清Gas、EGF、5-HT及DA水平进行统计及比较。结果经研究比较发现,C组的呕吐发生率低于A组及B组,呕吐次数少于A组及B组,呕吐潜伏期长于A组及B组,与A组及B组比较,C组的血清Gas、5-HT及DA水平较低,血清EGF较高,经比较,P<0.05或P<0.01,有显著性差异或有非常显著性差异。结论盐酸昂丹司琼对呕吐家兔胃肠激素和神经递质水平的影响较大,改善了化疗造成的呕吐,值得进一步研究及探讨。
作者 高源 高鸿
出处 《中国医药指南》 2013年第7期545-546,共2页 Guide of China Medicine
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  • 1蔡定芳,沈自尹,张玲娟,陈晓红,堀口贞次郎,小岛晓,井上昌辉.右归饮对皮质酮大鼠下丘脑单胺类递质含量以及体重饮食摄水的影响[J].中国中西医结合杂志,1995,15(12):728-731. 被引量:23
  • 2[1]Wiser W,Berger A.Practical management of chemotherapy-induced nausea and vomiting.Oncology Williston Park),2005,19:637
  • 3[2]Aapro M,et al.Palonosetron is effective in preventing acute and delayed chemotherapy-induced nausea and vomiting in patients recieving highly emetogenic chemotherapy (HEC)[Abstract].Support Care Cancer,2003,11:A17
  • 4[3]Jordan K,Kasper C,Schmoll HJ.Chemotherapy-induced nausea and vomiting:Current and new standards in the antiemetic prophylaxis and treatment.Eur J Cancer,2005,41:199
  • 5[4]Roila F,Donati D,Tamberi S,et al.Delayed emesis:Incidence,pattern,prognostic factors and optimal treatment.Support Care Cancer,2002,10:88
  • 6[5]website:http//www.mascc.org.Multinational association for supportive care in cancer.Consensus Conference on antiemitic therapy Perugia,2004,March 29-31
  • 7[6]Hesketh PJ,Kris MG,Grunberg SM,et al.Proposal for classifying the acute emetogenicity of cancer chemotherapy.J Clin Oncol,1997,15:103
  • 8[7]Morrow GR.The effect of a susceptibility to motion sickness on the side effects of cancer chemotherapy.Cancer,1985,55:2766
  • 9[8]Osoba D,Zee B,Pater J,et al.Determinants of postchemotherapy nausea and vomiting in patients with cancer.Quality of Life and Symptom Control Committees of the National Cancer Institute of Canada Clinical Trials Group.J Clin Oncol,1997,15:116
  • 10[9]Doherty KM.Closing the gap in prophylactic antiemetic therapy:Patient factors in calculating the emetogenic potential of chemotherapy.Clin J Oncol Nurs,1999,3:113

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