新生儿低血糖脑损伤临床特征40例分析

The clinical features of neonatal hypoglycemia brain damage

目的对新生儿低血糖脑损伤的临床特征进行分析和总结。方法回顾性分析低血糖患儿脑损伤组与非脑损伤组的临床资料。结果低血糖持续时间、反复发作>12h、新生儿惊厥发生率等,脑损伤组高于非脑损伤组,P<0.01。低血糖脑损伤组治疗24h后血糖恢复正常者(55%)低于与非脑损伤组(75%),P<0.01。结论新生儿低血糖脑损伤的治疗应着重早期的监测和预防,无论是有或无症状的低血糖患儿均应早期治疗,减少脑细胞的损害。

Objective To analyse the clinical features of neonatal hypoglycemia brain damage. Methods The clinical data of 40 children with hypoglycemia were analysed retrospectivly. Results Brain damage group than non-brain injury group in the duration of hypoglycemia,recurrent episodes 〉 12h and neonatal seizures （P 〈 0. 01 ）. After 24h of treatment, blood glucose returned to normal in non-brain injury group than that in brain damage group （ P 〈 0. 01 ）. Conclusion Neonatal hypoglycemic brain damage must be early detection and prevention.