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胃癌患者血清VEGF和MMP-3检测的临床意义 被引量：2

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摘要 运用ELISA法检测18例健康人、52例胃癌患者术前VEGF和MMP-3的含量。胃癌患者血清VEGF和MMP-3水平明显高于健康者,并与浸润深度、淋巴结转移、远处转移、临床分期密切相关(P<0.05);与患者年龄、性别、肿瘤分化程度无关(P>0.05)。健康者血清VEGF和MMP-3含量没有相关性(P>0.05),但在胃癌患者血清中两者存在明显相关性(P<0.05)。VEGF、MMP-3参与肿瘤的发生发展,与肿瘤的侵袭、转移密切相关,检测血清中VEGF、MMP-3的水平有助于胃癌的临床治疗和预后评估。
作者 许威 刘宏斌 韩晓鹏 李洪涛 朱万坤
机构地区 兰州大学第二临床医学院普通外科 兰州军区兰州总医院普外科
出处 《中国现代普通外科进展》 CAS 2013年第4期330-331,334,共3页 Chinese Journal of Current Advances in General Surgery
关键词 胃肿瘤·基质金属蛋白酶3·血管内皮生长因子
分类号 R735.2 [医药卫生—肿瘤]
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参考文献11

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中国现代普通外科进展
2013年 第4期

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