不稳定心绞痛患者焦虑抑郁状态分析

Influencing factors of anxiety and depression in patients with unstable angina

目的探讨不稳定心绞痛(unstable angina,UA)患者焦虑抑郁状态及相关影响因素。方法连续入选2011年1月至2012年1月首都医科大学附属北京安贞医院心内科住院不稳定心绞痛患者204例,采用综合医院焦虑抑郁评分量表行心理测评,评价焦虑、抑郁的发生率,对性别、受教育程度、医保类型等影响因素进行分析。结果 204例患者中,焦虑患者67例,占32.8%,抑郁患者46例,占22.5%。女性、合并高血压史者焦虑发生率更高(P<0.05);女性、初中及以下学历、报销比例≤40%、合并糖尿病者抑郁发生率更高(P<0.05)。Logistic回归分析结果显示初中及以下学历和合并糖尿病史是发生抑郁的主要影响因素。结论对于合并焦虑抑郁状态的UA患者,应引起临床医师重视,尽早给予心理干预,改善预后。

Objective To investigate prevalence and influential factors of anxiety and depression in patients with unstable angina （UA）. Methods Data of 204 patients with UA who were admitted in our hospital from January of 2011 to January of 2012 were collected. All the subjects were assessed with Hospital Anxiety and Depression Scale. Comparative analysis of influencing factors such as age, gender, educational level, type of health insurance, etc. was conducted. Results Of all the subjects, 67 cases （32.8%） were identified as anxiety, 46 （22.5%） as depression. Patients of UA with anxiety were more frequently seen in femal, with history of hypertension. Patients of UA with depression were more frequently seen in female, lower education level, those whose medical reimbursement covered ≤40% of medical expenses and with history of diabetes. Multivariate logistic regression analysis showed lower education level and with history of diabetes were the major risk factors on depression. Conclusion Patients with UA had high prevalence of anxiety and depression disorders. More attention should be paid to this phenomenon.