垂体柄阻断综合症的MRI诊断与临床特点分析

MRI Diagnosis and Clinical Analysis of Pituitary Stalk Interruption Syndrome

目的分析总结垂体柄阻断综合症(PSIS)的临床特点与MRI表现,提高对该病的认识和诊断水平。方法回顾性分析5例诊断为垂体柄阻断综合症的临床特点与MRI表现。结果 MRI显示垂体柄缺如4例,垂体柄明显变细1例,垂体后叶异位5例,垂体前叶变小5例。5例患者均表现生长发育迟缓,胰岛素低血糖兴奋试验提示生长激素缺乏,伴多种腺垂体激素缺乏。结论垂体MRI是诊断本病最重要和最直接的检查,PSIS具有特征性MRI表现,结合临床表现和实验室检查可做出准确诊断。

Objective To enhance the understanding and the diagnostic accuracy of pituitary stalk interruption syndrome by analyzing and summarizing the MRI features. Methods Retrospective analysis was performed according to the clinical and imaging data of 5 pa- tients with pituitary stalk interruption syndrome. Results With MRI examination, the pituitary stalk were not shown in 4 cases, obviously thin pituitary stalk in 1 cases, ectopic posterior lobe and decreased anterior lobe in 5 cases, Growth retardation, lack of growth hormone and multiple adenohypophysial hormone was found in all cases. Conclusion MRI is the most important and the most direct method for the diagnosis of pituitary stalk interruption syndrome. PSIS has characteristic MRI manifestations which can be diag- nosed definitely combined with clinical feature and laboratory examination.